Experience

My Journey Through Computational Biology: From Genomics to Modern AI

2024 — 2026 work

Researcher

Ideker Lab, UC San Diego, USA

Developed deep-learning approaches for modelling and transferring perturbation responses across biological contexts, with a focus on biologically meaningful prediction and evaluation.

Deep-LearningPerturbation ModellingBenchmarkingModern AI
2022 — Present work

MSCA Doctoral Fellow

GoldLab, University College Dublin, Ireland

Marie Skłodowska-Curie Actions Fellowship — competitive EU-wide award

Developed computational and experimental approaches to identify and characterise regulatory non-coding RNA targets using functional genomics, CRISPR perturbation, and multi-omics data.

lncRNA DiscoveryRegulatory GenomicsMulti-omicsCRISPR Screens
2019 — 2022 work

Bioinformatician

Onkoslab, National Centre for Biological Sciences (NCBS), India

Applied computational genomics and machine learning to study cancer regulatory mechanisms, tumour heterogeneity, and biomarkers of immunotherapy response across bulk and single-cell datasets.

Cancer GenomicsMulti-omicNextflowFAIR principles
Graduate education

MSc, Bioinformatics & Applied Biotechnology

Institute of Bioinformatics and Applied Biotechnology (IBAB), India

Foundations in bioinformatics, genomics, and applied biotechnology.

BioinformaticsProgrammingBench skillsGenomics
RESEARCH PROJECTS

HyperMAP

PyTorch meta-learning framework that transfers gene and drug perturbation responses across biological contexts.

PyTorchDeep-LearningPerturbation

TransCistor

Cis-regulatory lncRNA discovery framework characterising 268 human and 134 mouse regulatory targets at controlled false-discovery rates.

lncRNARegulatory GenomicsR

p53 mutant landscape

Differential chromatin accessibility landscape of gain-of-function mutant p53 tumours.

TCGACancer GenomicsMulti-omics

Immunoproteasome

Random-forest models evaluating pan-cancer immunoproteasome activity as a predictor of immunotherapy response, benchmarked against established markers.

TCGAImmunotherapyCancer GenomicsBiomarkers
Consortia & Collaborations

FANTOM6 — RNA–DNA Interactome

Investigating regulatory elements involved in RNA–DNA interactions. Exploring links between DNA–DNA and RNA–DNA interaction landscapes.

Multi-omicsConsortiumRADICL-seqRNA regulation

NIH — Small-Cell Lung Cancer scRNA-seq

Pilot analysis of single-cell SCLC data to investigate how the local liver microenvironment influences tumour cell evolution.

scRNA-seqTumour Evolutionsc-RNASCLC